Düsseldorf International Airport is the closest arrival point if you're visiting by plane. It lies about 8 kilometres from the Old Town. Both Cologne Bonn Airport and Dortmund Airport can be reached within 90 minutes.
The main connection between Düsseldorf International Airport and the city centre is the S-Bahn line running from beneath the main terminal.
From the Central Station you can hop aboard ICE (InterCityExpress) trains to neighbouring countries, for example the Netherlands, while the local light rail system ensures that Düsseldorf is well connected to other cities in the area, like Cologne, Duisburg, Wuppertal, Aachen and Dortmund.